rongsheng wang temple free sample
Zhang Y, Fang C,Wang RE, Wang Y, Guo H, Guo C, Zhao L, Li S, Li X, Schultz PG, Cao YJ, Wang F. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):15889-15894.
Wissler HL, Ehlerding EB, Lyu Z, Zhao Y, Zhang S, Eshraghi A, Buuh ZY, McGuth JC, Guan Y, Engle JW, Bartlett SJ, Voelz VA, Cai W,Wang RE. Mol Pharm. 2019 May 6;16(5):2028-2036.
37.Benjamin L. Prather+, Shuyue Ji+, Yue Zhao, Femil Joseph Shajan, Mi Zhao, Zakey Yusuf Buuh, Robert Maloney, Rui Zhang, Carson Cohen, Rongsheng E. Wang*, "Fluorine-thiol displacement probes for acetaminophen"s hepatotoxicity", Acta Pharmaceutica Sinica B, 2023, 13(1), 204-212. doi:
36. Carson Cohen+, Todd R. Lewis+, Rongsheng E. Wang*, "The role of post-translational modifications in cancer", Handbook of Cancer and Immunology. 2022, Springer, Cham.doi: 10.1007/978-3-030-80962-1_288-1
35. Md Shafiqul Islam, Samuel L. Junod, Si Zhang, Zakey Yusuf Buuh, Yifu Guan, Mi Zhao, Kishan H. Kaneria, Parmila Kafley, Carson Cohen, Robert Maloney, Zhigang Lyu, Vincent A. Voelz, Weidong Yang, Rongsheng E. Wang*,"Unprotected peptide macrocyclization and stapling via a fluorine-thiol displacement reaction", Nature Communications, 2022, 13, 350.doi: 10.1038/s41467-022-27995-5
34. Tiantian Li, Yuhan Zhang, Xiangqian Jia, Yanchao Ding, Mengling Wu, Luyao Wang, Hang Chen, Rui Zhu, Rongsheng E. Wang, Chenjun Shen, Feng Wang, Juanjuan Du*, "Rational design of bispecific antibody drug conjugates with balanced potency and selectivity", , submitted.
33.Jinfeng Kang, Todd R. Lewis, Alexander C. Gardner, Rodrigo B. Andrade, Rongsheng E. Wang*,"Semi-Syntheses and Interrogation of Indole-Substituted Aspidosperma Terpenoid Alkaloids", Organic & Biomolecular Chemistry, 2022, 20, 3988-3997.
31. Robert Maloney+, Zakey Yusuf Buuh+, Yue Zhao+, Rongsheng E. Wang*,"Site-specific antibody fragment conjugates for targeted imaging",Methods in Enzymology, 2020,638: 295-320. doi:10.1016/bs.mie.2020.02.023
30. Yuhan Zhang , Changming Fang , Rongsheng E. Wang , Ying Wang , Hui Guo , Chao Guo , Lijun Zhao , Shuhong Li , Xia Li , Peter G. Schultz*, Yu Joshua Cao , Feng Wang, "A tumor-targeted immune checkpoint blocker",Proceedings of the National Academy of Sciences U S A, 2019, 116(32):15889-15894. doi: 10.1073/pnas.1905646116.
29. Haley L. Wissler+, Emily B. Ehlerding+, Zhigang Lyu, Yue Zhao, Si Zhang, Anisa Eshraghi, Zakey Yusuf Buuh, Jeffrey C. McGuth, Yifu Guan, Jonahan W. Engle, Sarah J. Bartlett, Vincent A. Voelz, Weibo Cai, Rongsheng E. Wang*, "A site-specific immunoPET tracer to image PD-L1", Molecular Pharmaceutics, 2019, 16(5):2028-2036. doi: 10.1021/acs.molpharmaceut.9b00010.
28.Zhigang Lyu+, Lei Kang+, Zakey Yusuf Buuh, Dawei Jiang, Jeffrey McGuth, Juanjuan Du, Haley L. Wissler, Weibo Cai, Rongsheng E. Wang*, “A switchable site-specific antibody conjugate”, ACS Chemical Biology, 2018, 13(4):958-964. doi: 10.1021/acschembio.8b00107.
27. Zakey Yusuf Buuh, Zhigang Lyu, Rongsheng E. Wang*, “Interrogating the roles of post-translational modifications of non-histone proteins”,Journal of Medicinal Chemistry, 2017, 61(8):3239-3252. doi: 10.1021/acs.jmedchem.6b01817.
26. Xiaozhou Luo, Guangsen Fu, Rongsheng E. Wang, Xueyong Zhu, Claudio Zambaldo, Renhe Liu, Tao Liu, Xiaoxuan Lyu, Jintang Du, Weimin Xuan, Anzhi Yao, Sean A. Reed, Mingchao Kang, Yuhan Zhang, Hui Guo, Chunhui Huang, Peng-Yu Yang, Ian A. Wilson, Peter G. Schultz*, and Feng Wang*, “Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria”, Nature Chemical Biology, 2017,13(8):845-849. doi: 10.1038/nchembio.2405.
25. Rongsheng E. Wang, Ying Wang, Yuhan Zhang, Chase Gabrelow, Yong Zhang, Victor Chi, Qiangwei Fu, Xiaozhou Luo, Danling Wang, Sean Joseph, Kristen Johnson, Arnab Chatterjee, Timothy M. Wright, Van Nguyen-Tran, John Tejaro, Argyrios N. Theofilopoulos, Peter G. Schultz*, and Feng Wang*, “Rational design of a Kv1.3 channel blocking antibody as a selective immunosuppressant”, Proceedings of the National Academy of Sciences U S A., 2016, doi: 10.1073/pnas.1612803113
24. Xiaozhou Luo, Claudio Zambaldo, Tao Liu, Yuhan Zhang, Weimin Xuan, Chen Wang, Sean A. Reed, Peng-yu Yang, Rongsheng E. Wang, Tsotne Javahishvili, Peter G. Schultz*, and Travis S. Young*, “Recombinant thiopeptides containing noncanonical amino acids”, Proceedings of the National Academy of Sciences U S A., 2016, 113(13): 3615-3620
23. Renhe Liu, Rongsheng E. Wang, Feng Wang*, “Antibody-Drug Conjugates for Non-oncological Indications”, Expert Opinion on Biological Therapy,2016, 16 (5): 591-593
22. Xiaozhou Luo, Tao Liu, Ying Wang, Haiqun Jia, Yuhan Zhang, Dawna Caballero, Juanjuan Du, Rongsheng E. Wang, Danling Wang, Peter G. Schultz* and Feng Wang*, “An Epitope-Specific Respiratory Syncytial Virus Vaccine based on an Antibody Scaffold”, Angewandte ChemieInternational Edition,2015, 54 (48): 14531-14534
21. Rongsheng E. Wang+,Tao Liu+, Ying Wang, Yu Cao, Jintang Du, Xiaozhou Luo, Vishal Deshmukh, Chan Hyuk Kim, Brian R. Lawson, Matthew S. Tremblay, Travis S. Young, Stephanie A. Kazane*, Feng Wang*, Peter G. Schultz*, “An Immunosuppressive Antibody-Drug Conjugate”, Journal of The American Chemical Society, 2015, 137 (9): 3229–3232
20. Yu Cao, Jun Y. Axup,Jennifer S. Y. Ma, Rongsheng E. Wang, Seihyun Choi, Virginie Tardif, Reyna K. V. Lim, Holly M. Pugh, Brian R. Lawson, Gus Welzel, Stephanie A. Kazane, Ying Sun, Feng Tian, Shailaja Srinagesh, Tsotne Javahishvili, Peter G. Schultz*, Chan Hyuk Kim*, “Multiformat T-Cell-Engaging Bispecific Antibodies Targeting Human Breast Cancers”, Angewandte Chemie International Edition, 2015, 54(24):7022-7027
19. Tao Liu, Guangsen Fu, Xiaozhou Luo, Yan Liu, Ying Wang, Rongsheng E. Wang, Peter G. Schultz *, Feng Wang*, “Rational Design of Antibody Protease Inhibitors”, Journal of The American Chemical Society, 2015, 137(12): 4042-4045
18. Rongsheng E. Wang*, Yin Zhang, Ling Tian, Weibo Cai, Jianfeng Cai, “Antibody-based Imaging of HER-2: Moving into the Clinic”, Current Molecular Medicine, 2013, 13(10): 1523-1537
17. Rongsheng E. Wang+, Ling Tian+, Yie-Hwa Chang*, “A Homogeneous Fluorescent Sensor for Human Serum Albumin”, Journal of Pharmaceutical and Biomedical Analysis, 2012, 63: 165-169
16. Ling Tian+, Rongsheng E. Wang+, Ying Fei, Yie-Hwa Chang*, “A Homogeneous Fluorescent Assay for cAMP-Phosphodiesterase Enzyme Activity”, Journal of Biomolecular Screening, 2012, 17(3): 409-414
15. Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang*, “Molecular PINCERs for Biomarker Analysis and Their Potential Application in HCV Diagnosis”, Antiviral Therapy, 2012, 17(7 Pt B): 1437-1442
14. Rongsheng E. Wang*,Frankie Costanza, Youhong Niu, Haifan Wu, Yaogang Hu, Whitney Hang, Yiqun Sun, Jianfeng Cai*, “Development of Self-Immolative Dendrimers for Drug Delivery and Sensing”, Journal of Controlled Release, 2012, 159(2): 154-163
13.Haifan Wu, Youhong Niu, Shruti Padhee, Rongsheng E. Wang, Yaqiong Li, Qiao Qiao, Ge Bai, Chuanhai Cao, Jianfeng Cai*, “Design and Synthesis of Unprecedented Cyclic γ-AApeptides for Antimicrobial Development”, Chemical Science, 2012, 3(8): 2570-2575
12. Rongsheng E. Wang, Youhong Niu, Haifan Wu, Yaogang Hu, Jianfeng Cai*, “Development of NGR-Based Anti-Cancer Agents for Targeted Therapeutics and Imaging”, Anticancer Agents in Medicinal Chemistry, 2012, 12(1): 76-86
11. Ge Bai, Shruti Padhee, Youhong Niu, Rongsheng E. Wang, Qiao Qiao, Robert Buzzeo, Chuanhai Cao*, Jianfeng Cai*, “Cellular Uptake of an α-AApeptide”, Organic and Biomolecular Chemistry, 2012, 10(6): 1149-1153
10. Youhong Niu+, Rongsheng E. Wang+,* Haifan Wu,a Jianfeng Cai,* “Recent development of small antimicrobial peptidomimetics, Future Medicinal Chemistry, 2012, 4(14): 1853-1862
9. Youhong Niu, Ge Bai, Haifan Wu,Rongsheng E. Wang, Qiao Qiao, Shruti Padhee, Robert Buzzeo, Chuanhai Cao*, Jianfeng Cai*, “Cellular Translocation of a γ-AApeptide Mimetic of Tat Peptide”, Molecular Pharmaceutics, 2012, 9(5): 1529-1534
8. Yaogang Hu, Mohamad Nassir Amin, Shruti Padhee, Rongsheng E. Wang, Archana Mattew, Jianfeng Cai*, “Lipidated α-AApeptides With Improved Antimicrobial Activity”, ACS Medicinal Chemistry Letter, 2012, 3(8): 683-686
7. Rongsheng E. Wang, Raj K. Pandita, Jianfeng Cai, Clayton R. Hunt, John Stephen Taylor*, “Inhibition of Heat Shock Transcription Factor Binding by a Linear Polyamide Binding in an unusual 1:1 Mode”, ChemBioChem, 2012, 13(1): 97-104
6. Rongsheng E. Wang, Youhong Niu, Haifan Wu, Mohamad Nassir Amin, Jianfeng Cai*, “Development of NGR Peptide-Based Agents for Tumor Imaging”, American Journal of Nuclear Medicine and Molecular Imaging, 2011, 1(1): 36-46
5. Rongsheng E. Wang, Yin Zhang, Jianfeng Cai, Weibo Cai, Ting Gao*, “Aptamer-Based Fluorescent Biosensors”, Current Medicinal Chemistry, 2011, 18(27): 4175-4184
4. Rongsheng E. Wang, Clayton R. Hunt, Jiawei Chen, John-Stephen Taylor*, “Biotinylated Quercetin as an Intrinsic Photoaffinity Proteomics Probe for the Identification of Quercetin Target Proteins”, Bioorganic and Medicinal Chemistry, 2011, 19(16): 4710-20
3. Rongsheng E. Wang*, Haifan Wu, Youhong Niu, Jianfeng Cai*, “Improving the Stability of Aptamers by Chemical Modification”, Current Medicinal Chemistry, 2011, 18(27): 4126-4138
2. Rongsheng E. Wang*, “Targeting Heat Shock Proteins 70/90 and Proteasome for Cancer Therapy”, Current Medicinal Chemistry, 2011, 18(27): 4250-4264
1. Rongsheng E. Wang, Jeffrey L.-F. Kao, Carolyn A. Hilliard, Raj K. Pandita, Joseph L. Roti Roti, Clayton R. Hunt, John-Stephen Taylor*, “Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin Derivatives”, Journal of Medicinal Chemistry, 2009, 52(7): 1912-21
1. Youhong Niu+, Yaogang Hu+, Rongsheng E. Wang+, Xiaolong Li+, Haifan Wu, Jiandong Chen, Jianfeng Cai, “AApeptides as a New Class of Peptidomimetics to Regulate Protein-Protein Interactions”, protein interaction / Book 1, InTech press, (edited by Jianfeng Cai and Rongsheng E Wang)
For evaluation of Axin peptide analogues, DLD-1 cells were cultured in 96-well flat bottom plates up to 70–80% confluency and were transfected with 200 ng M50 TOPFlash plasmid (a gift from Professor Raymond Habas, Temple Biology) and 50 ng pRL-TK plasmid (Promega). 12 h after transfection, cells were treated with DMSO vehicle or 15 μM of Axin peptide analogues for another 24 h. Luciferase activity was measured using the Dual-Glo luciferase assay kit (Promega) on a Biotek Synergy H1 plate reader using the Gen5 software. Data were processed as firefly: Renilla luciferase ratio for each control or treatment group, and were further normalized against the vehicle control group (100%) as the Relative Activities.
Wang’s bio according to Chine.de - An Encyclopaedia on Chinese History, Literature and ArtWang Lang 王朗 (died 228 CE) courtesy name Jingxing 景興, was a high minister and Confucian scholar of the early years of the Wei period. He came from Tan 郯 in the commandery of Donghai 東海 (today"s Tancheng 郯城, Shandong) and was, as proficient in the Confucian Classics, appointed gentleman of the interior (langzhong 郎中), then magistrate of Ziqiu 菑丘. In the turmoils of the Yellow Turban rebellion 黃巾起義 he became a follower of the warlord Tao Qian 陶謙, who promoted his appointment as governor (taishou 太守) of the commandery of Guiji 會稽. This region was contested, and Wang Lang had to ward off the warlord Sun Ce 孫策. The warlord Cao Cao 曹操 therefore decided to offer him the post of Grand Master of Remonstrance (jianyi dafu 諫議大夫), and made him concurrently military administrator of the Ministry of Works (can sikong junshi 參司空軍事). When Cao Cao, as factual regent of the empire, was made king of Wei 魏, Wang Lang was made governor of Weijun 魏郡 and "military libationer" (? jun jijiu 軍祭酒), later promoted to Chamberlain for the Palace Revenues (shaofu 少府), Chamberlain for Ceremonials (fengchang 奉常) and Chamberlain for Law Enforcement (dali 大理). When Cao Pi 曹丕 (Emperor Wen of Wei 魏文帝, r. 220-226) assumed the title of emperor, Wang Lang was appointed Censor-in-chief (yushi dafu 御史大夫) and given the title of neighbourhood marquis of Anling 安陵亭侯. Somewhat later he was made Minister of Works (sikong 司空) and promoted to Marquis of Leping Village 樂平鄉侯. Emperor Ming 魏明帝 (r. 226-239 CE) conferred upon him the title of Marquis of Lanling 蘭陵侯 and appointed him Minister of Education (situ 司徒). His posthumous title was Marquis Cheng 蘭陵成侯. Wang Lang wrote commentaries to the Classics Chunqiu 春秋, Xiaojing 孝經 and Zhouguan 周官 (Zhouli 周禮), and wrote numerous memorials to the throne. Most of his writings are lost.
In Romance of the Three Kingdoms Wang LangIn the 14th-century historical novel Romance of the Three Kingdoms, Wang Lang died at the age of 76 in 228. Despite his age, he led a group of soldiers and set up camp to do battle with Zhuge Liang. In the novel, Cao Zhen was defeated by Zhuge Liang. Cao Zhen called for his subordinates to help, and Wang Lang decided to try and persuade him to surrender (even though Guo Huai was sceptical that it would succeed) and engaged Zhuge Liang in a debate, but was soundly defeated. Zhuge Liang among other things scolded him as a dog and a traitor, from the shock of which he fell off his horse and died on the spot. There is no record of this in history, and instead, it is said that he merely sent a letter to Zhuge Liang recommending that he surrender. The letter was ignored.
The birth of mantis boxing has been well debated. Some claim it was a product of the Song dynasty (960–1279), while others place it in the Ming dynasty (1368-1644). The evidence however points to the Qing dynasty (1644-1912) as the likely period of birth, and Wang Lang is a contributing factor to the evidence.
How did Wang Lang become entwined with the history of Praying Mantis Boxing (Tángláng Quán - 螳螂拳) almost 2 millennia later? Is this the same Wang Lang, or was there someone else who founded this boxing style who went by the same name? I believe these are one and the same.
Wang, as with many famous generals in Chinese history, was deified. He became a god especially to those villagers and communities in the region near his birth. There is even a statue of Wang Lang located in Shandong province. There is however no mention in historical records of Wang Lang practicing or teaching something known as - praying mantis boxing. Wang existed long before mantis boxing appeared in the second half of the Qing dynasty. So how did Wang become the progenitor of this style in the 18th or more likely, the 19th century? Who incorporated Wang Lang into the mantis lineage, and why?
Was it Wang Rong Sheng (王榮生, 1854-1926) founder of the ‘seven star’ branch of praying mantis boxing? Even though Rongsheng had a different teacher (Li San Jian, also not a mantis boxer) than the other mantis boxers under Liang Xuexiang? Wang Rongsheng’s shared surname with the famous deity is likely a mere coincidence. Perhaps Wang Rongsheng’s family lineage tree did trace all the way back to the Han dynasty warlord. This is all conjecture. It is unknown who tied Wang Lang to Tanglangquan"s history, but the time period can be narrowed down by other cultural factors which existed in Shandong province in the late 19th century, and from these a reasonable explanation of how this connection was made can be discerned.
At this time opera and folklore was highly popularized in local villages, towns. Famous stories were acted out such as Water Margin, Journey to the West, The Enfeoffment of the Gods, and The Romance of the Three Kingdoms. Wang Lang’s exploits were part of these tales, and Wang was a hero that would have had personal meaning to the locals of Shandong as he hailed from their homeland.
Additionally, Esherick writes:“There was one paramount occasion when these temples became a focus for community activity: the temple fair, held annually at temples in larger villages or market towns. The name for these - “inviting the gods to a performance” (ying-shen sai hui). The center of attention was an opera, for the benefits of the gods.”
It important to capture this in the entirety of what Esherick writes next:“Above all, these occasions were welcomed for the relief they provided from the dull monotony of peasant toil. Relatives would gather from surrounding villages. Booths would be set up to sell food and drink, and provide for gambling. The crowds and opera created an air of excitement welcome to all. But the statement of community identity provided by opera and temple was also extremely important. It is important, too, that the gods were not only part of the audience: many of the most popular dramatic characters---borrowed from novels which blended history and fantasy---had also found places in the popular religious pantheon. Since few villages had resident priests, and few peasants received religious instruction at larger urban temples, it was principally these operas that provided substantive images for a Chinese peasant’s religious universe. This is why sectarian borrowing from popular theatre is so important. To the extent that sectarian groups incorporated gods of the theatre, they brought themselves into the religious community of the village---rather than setting themselves apart as a separate congregation of the elect.
Was Wang Rong Sheng spirit boxing with the deity Wang Lang? Was it one of his friends, Jiang, Song, or Hao, the founders of the other branches of mantis boxing (plum blossom praying mantis boxing, supreme ultimate praying mantis boxing, supreme ultimate plum blossom praying mantis boxing) that emerged around this time? All of them acting together perhaps? Or was this something their teacher Liang Xuexiang being wiser, older, educated, and well traveled used to inspire the younger boxers under his charge?
Whatever the reasons for Wang Lang being assigned attributions as the creator of praying mantis boxing we can most likely determine from the popularity of spirit boxing and the trend in the late 1800’s that this period in time during the late Qing, when shen-quan was revitalized, was the period when Wang was incorporated into the lineage. We can view this same occurrence in Eagle Claw Boxing around the same time period to the northwest in Hebei province. Yue Fei, another famous general in Chinese history is credited with founding that style. Yue Fei also had no definitive connection to eagle claw boxing prior to this time period in the Qing.
In the second generation of the lineage charts in both mantis boxing and eagle claw, are similarly obscured. In both styles there is no definitive link between the founder and the next verified carrier of the torch. The two have very similar discrepancies within their histories after these deities supposedly invented them. The oral records claim the styles after being invented, then went into the Shaolin temple almost 900km (560 miles) to the west, and three to four weeks walking distance away from Yantai where mantis existed centuries later. There is no known record of mantis, or eagle claw styles being part of the Shaolin boxing system. Are we to believe these styles, if they did exist at Shaolin for a time, were suddenly spit back out hundreds of years later back in Shandong or Hebei?
It is much more plausible that these military legends, Yue Fei, and Wang Lang, were brought about into these styles in the late Qing as spirit boxing rose to prominence once more amongst the martial artists of the time. As we’ll see in the time period of Li Bingxiao (李炳霄 1731-1813 estimated), during the ‘High Qing’, martial artists did not stay with one teacher. They rather learned from a multitude of sources similar to a modern day university student, thus making it extremely difficult for the concept of ‘styles’ to gain root during this time unlike a few decades later.
This can explain the lack of history in between the founders, and the verifiable practitioners of these arts in the late Qing. Why they suddenly ‘disappear’ into temples in their lineage charts. Only to then reappear centuries later with traceable roots. It explains an oral history in mantis boxing that this style was an amalgamation of 18 different ‘styles’. This is far more believable and easier to comprehend in the realm of martial arts if each of these 18 ‘styles’ was a technique or two from each independent source the practitioner learned from. Finally, it can further explain why prior to the 18th and 19th century, there is no definable lineage for these arts.
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1.Zhang T, Nong J, Alzahrani N, Wang Z, Meier T, Yang DG, Ke Y, Zhong Y*, Fu J*. “Self-Assembly of DNA Minocycline Complexes by Metal Ions with Controlled Drug Release”. ACS Applied Materials & Interfaces. 11: 29512-29521, 2019. *Co-corresponding authors
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Rongsheng (Ross) Wang, chemistry, Temple University – A Fluorine Displacement Based Bioorthogonal Labeling Approach to Interrogate Non-Histone Substrates of “Histone” Deacetylases