pup joint wikipedia free sample

The stifle joint (often simply stifle) is a complex joint in the hind limbs of quadruped mammals such as the sheep, horse or dog. It is the equivalent of the human knee and is often the largest synovial joint in the animal"s body. The stifle joint joins three bones: the femur, patella, and tibia. The joint consists of three smaller ones: the femoropatellar joint, medial femorotibial joint, and lateral femorotibial joint.

The stifle joint consists of the femorotibial articulation (femoral and tibial condyles), femoropatellar articulation (femoral trochlea and the patella), and the proximal tibiofibular articulation.

The joint is stabilized by paired collateral ligaments which act to prevent abduction/adduction at the joint, as well as paired cruciate ligaments. The cranial cruciate ligament and the caudal cruciate ligament restrict cranial and caudal translation (respectively) of the tibia on the femur. The cranial cruciate also resists over-extension and inward rotation, and is the most commonly damaged stifle ligament in dogs.

"Cushioning" of the joint is provided by two C-shaped pieces of cartilage called menisci which sit between the medial and lateral condyles of the distal femur and the tibial plateau. The main biomechanical function of the menisci is probably to divide the joint into two functional units—the "femoromeniscal joint" for flexion/extension movements and the "meniscotibial joint" for rotation—a function analogous to that of the disc dividing the temporomandibular (jaw) joint. The menisci also contain nerve endings which are used to assist in proprioception.

There are between one and four sesamoid bones associated with the stifle joint in different species. These sesamoids assist with the smooth movement of tendon/muscle over the joint. The most well-known sesamoid bone is the patella, more commonly known as the "knee cap". It is located cranially to the joint and sits in the trochlear groove of the femur. It guides the patellar ligament of the quadriceps over the knee joint to its point of insertion on the tibia. Caudal to the joint, in the dog for example, are the two fabellae, which lie in the two tendons of origin of gastrocnemius. Fourth, there is often a small sesamoid bone in the tendon of origin of popliteus in many species. Humans possess only the patella.

Drill pipe makes up the majority of the drill string back up to the surface. Each drill pipe comprises a long tubular section with a specified outside diameter (e.g. 3 1/2 inch, 4 inch, 5 inch, 5 1/2 inch, 5 7/8 inch, 6 5/8 inch). At each end of the drill pipe tubular, larger-diameter portions called the tool joints are located. One end of the drill pipe has a male ("pin") connection whilst the other has a female ("box") connection. The tool joint connections are threaded which allows for the mating of each drill pipe segment to the next segment.

Most components in a drill string are manufactured in 31 foot lengths (range 2) although they can also be manufactured in 46 foot lengths (range 3). Each 31 foot component is referred to as a joint. Typically 2, 3 or 4 joints are joined together to make a stand. Modern onshore rigs are capable of handling ~90 ft stands (often referred to as a triple).

Machine translation, like DeepL or Google Translate, is a useful starting point for translations, but translators must revise errors as necessary and confirm that the translation is accurate, rather than simply copy-pasting machine-translated text into the English Wikipedia.

You must provide copyright attribution in the edit summary accompanying your translation by providing an interlanguage link to the source of your translation. A model attribution edit summary is Content in this edit is translated from the existing Czech Wikipedia article at [[:cs:Anatomie psa domácího]]; see its history for attribution.

Deep pectoral: originates on the ventral sternum and inserts on the lesser tubercle of the humerus. It acts to extend the shoulder joint during weight bearing and flexes the shoulder when there is no weight. It is innervated by the caudal pectoral nerves.

Latissimus dorsi: originates on thoracolumbar fascia and inserts on the teres major tuberosity of the humerus. Its function is to flex the shoulder joint. It is innervated by the thoracodorsal nerve.

Infraspinatus: originates on the infraspinatus fossa and inserts on the greater tubercle of the humerus. It acts to extend and flex the shoulder joint. It is innervated by the suprascapular nerve.

Supraspinatus: originates on the supraspinous fossa and inserts on the greater tubercle of the humerus. It acts to extend and stabilize the shoulder joint. It is innervated by the suprascapular nerve.

Subscapularis: originates on the subscapular fossa and inserts on the greater tubercle of the humerus. It acts to rotate the arm medially and stabilize the joint. It is innervated by the subscapular nerve.

Coracobrachialis: originates on the coracoid process of the scapula and inserts on the crest of the lesser tubercle of the humerus. It acts to adduct, extend and stabilize the shoulder joint. It is innervated by the musculocutaneous nerve.

Common digital extensor: originates on the lateral epicondyle of the humerus and inserts on the distal phalanges. It acts to extend the carpus and joints of the digits 3, 4, and 5. It is innervated by the radial nerve.

Extensor carpi ulnar: originates on the lateral epicondyle of the humerus and inserts on the metacarpal 5 and the accessory carpal bone. It acts to abduct and extend the carpal joint. It is innervated by the radial nerve.

Abductor pollicis longus: originates on the ulna and inserts on metacarpal 1. It acts to abduct the digit and extend the carpal joints. It is innervated by the radial nerve.

Superficial digital flexor: originates on the medial epicondyle of the humerus and inserts on the palmar surface of the middle phalanges. It acts to flex the carpus, metacarpophalangeal and proximal interphalangeal joints of the digits. It is innervated by the median nerve.

Deep digital flexor: originates on the medial epicondyle of the humerus and inserts on the palmar surface of the distal phalanx. It acts to flex the carpus, metacarpophalangeal joints, and the proximal and distal interphalangeal joints of the digits. It is innervated by the median nerve.

The domestic dog compared to the wolf shows the greatest variation in the size and shape of the skull (Evans 1979) that range from 7 to 28 cm in length (McGreevy 2004). Wolves are dolichocephalic (long skulled) but not as extreme as some breeds of dogs such as greyhounds and Russian wolfhounds (McGreevy 2004). Canine brachycephaly (short-skulledness) is found only in domestic dogs and is related to paedomorphosis (Goodwin 1997). Puppies are born with short snouts, with the longer skull of dolichocephalic dogs emerging in later development (Coppinger 1995). Other differences in head shape between brachycephalic and dolichocephalic dogs include changes in the craniofacial angle (angle between the basilar axis and hard palate) (Regodón 1993), morphology of the temporomandibular joint (Dickie 2001), and radiographic anatomy of the cribriform plate (Schwarz 2000).

As crepuscular hunters, dogs often rely on their vision in low light situations: They have very large pupils, a high density of rods in the fovea, an increased flicker rate, and a tapetum lucidum.: page139

, Santos, A "Puppy and Dog Care: An Essential Puppy Training Guide", 2015 Amazon Digital Services, Inc. [1] Archived 24 June 2015 at the Wayback Machine

Arthritis is a term often used to mean any disorder that affects joints.Symptoms generally include joint pain and stiffness.swelling, and decreased range of motion of the affected joints.

There are over 100 types of arthritis.osteoarthritis (degenerative joint disease) and rheumatoid arthritis.autoimmune disorder that often affects the hands and feet.gout, lupus, fibromyalgia, and septic arthritis.rheumatic disease.

Treatment may include resting the joint and alternating between applying ice and heat.loss and exercise may also be useful.ibuprofen and paracetamol (acetaminophen).joint replacement may be useful.

There are several diseases where joint pain is primary, and is considered the main feature. Generally when a person has "arthritis" it means that they have one of these diseases, which include:

Pain, which can vary in severity, is a common symptom in virtually all types of arthritis.swelling, joint stiffness, redness, and aching around the joint(s).lupus and rheumatoid arthritis can affect other organs in the body, leading to a variety of symptoms.

Elements of the history of the disorder guide diagnosis. Important features are speed and time of onset, pattern of joint involvement, symmetry of symptoms, early morning stiffness, tenderness, gelling or locking with inactivity, aggravating and relieving factors, and other systemic symptoms. Physical examination may confirm the diagnosis or may indicate systemic disease. Radiographs are often used to follow progression or help assess severity.

Blood tests and X-rays of the affected joints often are performed to make the diagnosis. Screening blood tests are indicated if certain arthritides are suspected. These might include: rheumatoid factor, antinuclear factor (ANF), extractable nuclear antigen, and specific antibodies.

Osteoarthritis is the most common form of arthritis.wrists, feet, back, hip, and knee. In dogs, this includes the elbow, hip, stifle (knee), shoulder, and back. The disease is essentially one acquired from daily wear and tear of the joint; however, osteoarthritis can also occur as a result of injury. Osteoarthritis begins in the cartilage and eventually causes the two opposing bones to erode into each other. The condition starts with minor pain during physical activity, but soon the pain can be continuous and even occur while in a state of rest. The pain can be debilitating and prevent one from doing some activities. In dogs, this pain can significantly affect quality of life and may include difficulty going up and down stairs, struggling to get up after lying down, trouble walking on slick floors, being unable to hop in and out of vehicles, difficulty jumping on and off furniture, and behavioral changes (e.g., aggression, difficulty squatting to toilet).chondrocytes to maintain the structural integrity of cartilage.

Rheumatoid arthritis (RA) is a disorder in which the body"s own immune system starts to attack body tissues.cartilage which eventually results in erosion of two opposing bones. RA often affects joints in the fingers, wrists, knees and elbows, is symmetrical (appears on both sides of the body), and can lead to severe deformity in a few years if not treated. RA occurs mostly in people aged 20 and above. In children, the disorder can present with a skin rash, fever, pain, disability, and limitations in daily activities.

Bone erosion is a central feature of rheumatoid arthritis. Bone continuously undergoes remodeling by actions of bone resorbing osteoclasts and bone forming osteoblasts. One of the main triggers of bone erosion in the joints in rheumatoid arthritis is inflammation of the synovium, caused in part by the production of pro-inflammatory cytokines and receptor activator of nuclear factor kappa B ligand (RANKL), a cell surface protein present in Th17 cells and osteoblasts.

Lupus is a common collagen vascular disorder that can be present with severe arthritis. Other features of lupus include a skin rash, extreme photosensitivity, hair loss, kidney problems, lung fibrosis and constant joint pain.

Gout is caused by deposition of uric acid crystals in the joints, causing inflammation. There is also an uncommon form of gouty arthritis caused by the formation of rhomboid crystals of calcium pyrophosphate known as pseudogout. In the early stages, the gouty arthritis usually occurs in one joint, but with time, it can occur in many joints and be quite crippling. The joints in gout can often become swollen and lose function. Gouty arthritis can become particularly painful and potentially debilitating when gout cannot successfully be treated.

Infectious arthritis is another severe form of arthritis. It presents with sudden onset of chills, fever and joint pain. The condition is caused by bacteria elsewhere in the body. Infectious arthritis must be rapidly diagnosed and treated promptly to prevent irreversible joint damage.

Psoriasis can develop into psoriatic arthritis. With psoriatic arthritis, most individuals develop the skin problem first and then the arthritis. The typical features are continuous joint pains, stiffness and swelling. The disease does recur with periods of remission but there is no cure for the disorder. A small percentage develop a severely painful and destructive form of arthritis which destroys the small joints in the hands and can lead to permanent disability and loss of hand function.

There is no known cure for arthritis and rheumatic diseases. Treatment options vary depending on the type of arthritis and include physical therapy, exercise and diet, orthopedic bracing, and oral and topical medications.Joint replacement surgery may be required to repair damage, restore function, or relieve pain.

In general, studies have shown that physical exercise of the affected joint can noticeably improve long-term pain relief. Furthermore, exercise of the arthritic joint is encouraged to maintain the health of the particular joint and the overall body of the person.

Individuals with arthritis can benefit from both physical and occupational therapy. In arthritis the joints become stiff and the range of movement can be limited. Physical therapy has been shown to significantly improve function, decrease pain, and delay the need for surgical intervention in advanced cases.

The female parent of puppies is referred to as the dam and the male parent is referred to as the sire. A litter consists of the puppies born from the same pregnancy. A whelp is a newborn puppy and giving birth to dogs is called whelping. Dogs commonly give birth in a

A person who intentionally mates dogs to produce puppies is referred to as a dog breeder. Line breeding is the planned breeding of dogs with their relatives. This is done to strengthen the appearance of specific desired traits in offspring. Line breeding is differentiated from inbreeding by excluding pairings between parents and offspring, and between full siblings. Outcrossing is the planned breeding between two unrelated dogs, used to increase genetic diversity in a breed and decrease genetic issues or abnormalities inherited from line breeding or inbreeding.

Initially, the ownership of working and purebred dogs, was a privilege of the wealthy. Today many people can afford to buy a dog. There are various reasons for people to breed dogs. Some people may have personal reasons, such as wanting to own or give away puppies, and are not interested in pedigree. Breeders may also breed dogs for profit, for show, because of an interest in a particular breed, or to correct some issue and improve the soundness of a breed. Responsible breeders take into consideration the temperament, as well as the health and appearance of the mating pair before breeding.

Breeders of purebred dogs can register the birth of a litter of puppies to a dog registry associated with a kennel club to record the parentage of the litter in stud books. Such registries maintain records of dogs’ lineage and are usually affiliated with kennel clubs, such as the AKC (American Kennel Club).purebred dog breeding. Access to records allows a breeder to analyze the pedigrees and anticipate traits and behaviors that may be passed onto offspring. Requirements for the breeding of registered purebreds vary between breeds, countries, kennel clubs and registries. Breeders have to abide by the rules of the specific organization to participate in its breed maintenance and development programs. The rules may apply to the health of the dogs, such as joint x-rays, hip certifications, and eye examinations; to working qualities, such as passing a special test or achieving at a trial; to general conformation, such as evaluation of a dog by a breed expert. However, many registries, particularly those in North America, are not policing agencies that exclude dogs of poor quality or health. Their main function is simply to register puppies born of parents which are themselves registered.

Inbreeding depression is the reduced survival and fertility of offspring of related individuals.inbreeding coefficient increased, litter size decreased and the percentage of stillborn puppies increased, thus indicating inbreeding depression.

Gresky C, Hamann H, Distl O (2005). "[Influence of inbreeding on litter size and the proportion of stillborn puppies in dachshunds]". Berl. Munch. Tierarztl. Wochenschr. (in German). 118 (3–4): 134–9. PMID 15803761.

Cruciate ligaments (also cruciform ligaments) are pairs of ligaments arranged like a letter X.joints of the body, such as the knee joint and the atlanto-axial joint. In a fashion similar to the cords in a toy Jacob"s ladder, the crossed ligaments stabilize the joint while allowing a very large range of motion.

Another structure of this type in human anatomy is the cruciate ligament of the dens of the atlas vertebra, also called "cruciform ligament of the atlas", a ligament in the neck forming part of the atlanto-axial joint.

In animals the two cruciate ligaments that cross the inside of the knee joint are referred to as the cranial cruciate (equivalent to anterior in humans) and the caudal cruciate (equivalent to the posterior in humans). The cranial cruciate ligament prevents the tibia from slipping forward out from under the femur.

Stifle injuries are one of the most common causes of lameness in rear limbs in dogs, and cruciate ligament injuries are the most common lesion in the stifle joint. A rupture of the cruciate ligament usually involves a rear leg to suddenly become so sore that the dog can barely bear weight on it.

Any bone spurs are removed and a large suture is passed around the fabella behind the knee through a drilled hole in the front of the tibia. This surgical procedure tightens the joint to prevent the drawer motion, and the suture that is put in place takes the job of the cruciate ligament for approximately 2 to 12 months after surgery. The suture will eventually break and the dog will have its own healed tissue that will hold the knee in place.

This surgery uses biomechanics of the knee joint and is meant to address the lack of success seen in the extracapsular repair surgery in larger dogs. A stainless steel bone plate is used to hold the two pieces of bone in place. This surgery is complex and typically costs more than the extracapsular repair.

Vanderperren K, Ghaye B, Snaps FR, Saunders JH (May 2008). "Evaluation of computed tomographic anatomy of the equine metacarpophalangeal joint". Am. J. Vet. Res. 69 (5): 631–8. doi:10.2460/ajvr.69.5.631. PMID 18447794. S2CID 24715289.

"Young, Wild & Free" is a pop-rap song, composed in the key of D major with a tempo of 100 beats per minute. Their voice ranges from a low of B2 to a high of A4.G-funk style of other songs by Dogg and Khalifa on the soundtrack, incorporating pop elements into the chorus.weed anthem, reminiscing "hazy times" and youth: "It"s like I"m 17 again/ Peach fuzz on my face/Lookin", on the case /Trying to get a hella taste", while the former in the following verses "Roll joints bigger than King Kong"s fingers/ And smoke them hoes down until they"re stingers."

"Young, Wild & Free" was performed live several times. Snoop Dogg and Wiz Khalifa began their High School Tour (a small, joint tour) in late 2011 to promote the soundtrack, and "Young, Wild & Free" was the closing song.Power 106"s Big Boy"s Neighborhood and performed the single.Coachella 2012; Khalifa joined him onstage with a giant joint.Fall Out Boy on the Boys of Zummer (North American) leg of the American Beauty/American Psycho Tour (2015), where he performed the single.

Credit card functionality is under development. In September 2016, the Reserve Bank of India (RBI) launched the eponymously named Bharat QR, a common QR code jointly developed by all the four major card payment companies – National Payments Corporation of India that runs RuPay cards along with MasterCard, Visa and American Express. It will also have the capability of accepting payments on the unified payments interface (UPI) platform.

Baldini, Gianmarco; Nai Fovino, Igor; Satta, Riccardo; Tsois, Aris; Checchi, Enrico (2015). Survey of techniques for the fight against counterfeit goods and Intellectual Property Rights (IPR) infringement. Luxembourg: European Commission. Joint Research Centre, Publications Office. ISBN 978-92-79-54543-6. OCLC 948769705.

Licking behavior has multiple causes and meanings and should not be simply interpreted as affection. Dogs that are familiar with each other may lick each other"s faces in greeting, then sniff any moist membranes where odors are strongest (i.e. mouth, nose, anal region, or urogenital region.) Mating behaviors are characterized by licking in a more vigorous manner than used during greetings.: 124 Licking can communicate information about dominance, intentions, and state of mind, and, like the yawn, is mainly a pacifying behavior. All pacifying behaviors contain elements of puppy behavior, including licking. Puppies lick themselves and their litter-mates as part of the cleaning process, and it appears to build bonds. Later in life, licking ceases to be a cleaning function and forms a ritualized gesture indicating friendliness.: 124–125 When stressed, a dog might lick the air, its own lips, or drop down and lick its paws or body.: 126Lip-licking and sniffing are also recognized as calming signals.

Whining and whimpers are short, high pitched sounds designed to bring the listener closer to show either fear or submission on the behalf of the whiner or whimperer. These are also the sounds that puppies make as pacifying and soliciting sounds.: 89

Genetic conditions are a problem in some dogs, particularly purebreds. For this reason many of the national kennel clubs require that dogs with certain genetic illnesses or who are deemed to be carriers cannot be registered. Some of the most common conditions include hip dysplasia seen in large breed dogs; von Willebrand disease a disease that affects platelets that is inherited in Doberman Pinschers; entropion a curling in of the eyelid seen in Shar Peis and many other breeds; progressive retinal atrophy inherited in many breeds; deafness and epilepsy known to be inherited in Belgian Shepherd Dogs, German Shepherd Dogs, Cocker Spaniels, and St. Bernards.Subaortic stenosis, or SAS, is a genetic ailment that causes a narrowing of the passage of blood between the heart and the aorta. This leads to heart problems and sometimes sudden death. It affects larger breeds such as the Newfoundland dog and the Golden Retriever.collies, the blue merle or harlequin coloring is actually the heterozygote of a partially recessive gene preventing proper development of the nervous system; therefore, if two such dogs are mated, on the average one quarter of the puppies will have severe genetic defects in their nervous systems and sensory organs ranging from deafness to fatal flaws.

Skin diseases are very common in dogs. Atopy, a chronic allergic condition, is thought to affect up to 10 percent of dogs.hot spots and pyoderma, both characterized by secondary bacterial infections, food allergy, ear infections, and flea allergy dermatitis. Canine follicular dysplasia is an inherited disorder of the hair follicles resulting in alopecia (baldness). Mange is an infectious skin disease caused by mites. Endocrine diseases such as hypothyroidism and Cushing"s syndrome can also manifest as skin problems like alopecia or recurring bacterial infections. Another class of integumentary malady is hygromas, a swelling typically on or near the elbow joint. Nutrition may also play a role in skin disease, as deficiencies in certain nutrients may result in scaling, redness, oiling, balding, and/or itching of the skin.dog skin disorders for specific nutrients that impacts skin)

Orthopedic diseases in dogs can be developmental, hereditary, traumatic, or degenerative. Because of the active nature of dogs, injuries happen frequently. One of the most common of these is an anterior cruciate ligament injury, a condition which often requires surgery. Bone fractures are a frequent occurrence in outdoor dogs due to trauma from being hit by cars. Degenerative joint disease is common in older dogs and is one of the most likely reasons for prescription of non-steroidal anti-inflammatory drugs.

Hereditary orthopedic diseases are mainly found in purebred dogs. Hip dysplasia is a common problem that primarily affects larger breeds. Hip dysplasia is a defect in the shape of the hip joint which can, depending on the degree of hip luxation, be quite painful to the dog as it ages. Over time it often causes arthritis in the hips. Dysplasia can also occur in the elbow joint. Luxating patellas can be a problem for smaller breeds. It can cause lameness and pain in the hind legs.

Ingestion can cause anxiety, muscle twitching, seizures, rapid heart rate, dilated pupils, hypersalivation, vomiting, diarrhea, and high fever due to the metaldehyde present. Treatment involves gastric lavage, intravenous fluid administration, and/or administration of activated charcoal.

Overdoses of vitamins can be harmful in dogs. As an example, calcium in excess can cause bone problems, especially in the large-breed dogs. Over-supplementation of vitamins A and D can cause vitamin toxicity in dogs.vitamin A can cause dehydration, joint pain and can also harm the blood vessels, while too much vitamin D can cause muscular atrophy, loss of appetite and many other health-related problems.

Animal control agencies in the United States and the ASPCA advise that dogs not intended for further breeding should be spayed or neutered so that they do not have undesired puppies.

Because of the overpopulation of dogs in some countries, puppies born to strays or as the result of accidental breedings often end up being killed in animal shelters. Spaying and neutering can also decrease the risk of hormone-driven diseases such as mammary cancer, as well as undesired hormone-driven behaviors. However, certain medical problems are more likely after surgery, such as urinary incontinence in femalesprostate cancer in males.

It is not essential for a female dog to either experience a heat cycle or have puppies before spaying, and likewise, a male dog does not need the experience of mating before neutering.

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.low red blood cell count, inflammation around the lungs, and inflammation around the heart.

While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors.immune system attacking the joints.joint capsule.bone and cartilage.X-rays and laboratory testing may support a diagnosis or exclude other diseases with similar symptoms.systemic lupus erythematosus, psoriatic arthritis, and fibromyalgia among others.

The goals of treatment are to reduce pain, decrease inflammation, and improve a person"s overall functioning.splints and braces, or the use of assistive devices.Pain medications, steroids, and NSAIDs are frequently used to help with symptoms.Disease-modifying antirheumatic drugs (DMARDs), such as hydroxychloroquine and methotrexate, may be used to try to slow the progression of disease.replace, or fuse joints may help in certain situations.

RA affects about 24.5 million people as of 2015.developed world with 5 and 50 per 100,000 people newly developing the condition each year.Augustin Jacob Landré-Beauvais (1772–1840) of Paris.rheumatoid arthritis is based on the Greek for watery and inflamed joints.

Arthritis of joints involves inflammation of the synovial membrane. Joints become swollen, tender and warm, and stiffness limits their movement. With time, multiple joints are affected (polyarthritis). Most commonly involved are the small joints of the hands, feet and cervical spine, but larger joints like the shoulder and knee can also be involved.: 1098 Synovitis can lead to tethering of tissue with loss of movement and erosion of the joint surface causing deformity and loss of function.fibroblast-like synoviocytes (FLS), highly specialized mesenchymal cells found in the synovial membrane, have an active and prominent role in these pathogenic processes of the rheumatic joints.

RA typically manifests with signs of inflammation, with the affected joints being swollen, warm, painful and stiff, particularly early in the morning on waking or following prolonged inactivity. Increased stiffness early in the morning is often a prominent feature of the disease and typically lasts for more than an hour. Gentle movements may relieve symptoms in early stages of the disease. These signs help distinguish rheumatoid from non-inflammatory problems of the joints, such as osteoarthritis. In arthritis of non-inflammatory causes, signs of inflammation and early morning stiffness are less prominent.nociceptive as opposed to neuropathic.: 1098

As the pathology progresses the inflammatory activity leads to tendon tethering and erosion and destruction of the joint surface, which impairs range of movement and leads to deformity. The fingers may develop almost any deformity depending on which joints are most involved. Specific deformities, which also occur in osteoarthritis, include ulnar deviation, boutonniere deformity (also "buttonhole deformity", flexion of proximal interphalangeal joint and extension of distal interphalangeal joint of the hand), swan neck deformity (hyperextension at proximal interphalangeal joint and flexion at distal interphalangeal joint) and "Z-thumb." "Z-thumb" or "Z-deformity" consists of hyperextension of the interphalangeal joint, fixed flexion and subluxation of the metacarpophalangeal joint and gives a "Z" appearance to the thumb.: 1098 The hammer toe deformity may be seen. In the worst case, joints are known as arthritis mutilans due to the mutilating nature of the deformities.

The rheumatoid nodule, which is sometimes in the skin, is the most common non-joint feature and occurs in 30% of people who have RA.necrotizing granuloma". The initial pathologic process in nodule formation is unknown but may be essentially the same as the synovitis, since similar structural features occur in both. The nodule has a central area of fibrinoid necrosis that may be fissured and which corresponds to the fibrin-rich necrotic material found in and around an affected synovial space. Surrounding the necrosis is a layer of palisading macrophages and fibroblasts, corresponding to the intimal layer in synovium and a cuff of connective tissue containing clusters of lymphocytes and plasma cells, corresponding to the subintimal zone in synovitis. The typical rheumatoid nodule may be a few millimetres to a few centimetres in diameter and is usually found over bony prominences, such as the elbow, the heel, the knuckles, or other areas that sustain repeated mechanical stress. Nodules are associated with a positive RF (rheumatoid factor) titer, ACPA, and severe erosive arthritis. Rarely, these can occur in internal organs or at diverse sites on the body.

The role of the circadian clock in rheumatoid arthritis suggests a correlation between an early morning rise in circulating levels of pro-inflammatory cytokines, such as interleukin-6 and painful morning joint stiffness.

Local osteoporosis occurs in RA around inflamed joints. It is postulated to be partially caused by inflammatory cytokines. More general osteoporosis is probably contributed to by immobility, systemic cytokine effects, local cytokine release in bone marrow and corticosteroid therapy.

RA primarily starts as a state of persistent cellular activation leading to autoimmunity and immune complexes in joints and other organs where it manifests.synovial membrane and joint damage, and the fibroblast-like synoviocytes play a key role in these pathogenic processes.T cell activation), and chronic inflammatory phase, with tissue injury resulting from the cytokines, IL–1, TNF-alpha, and IL–6.

This contributes to local inflammation in a joint, specifically the synovium with edema, vasodilation and entry of activated T-cells, mainly CD4 in microscopically nodular aggregates and CD8 in microscopically diffuse infiltrates.dendritic cells function as antigen-presenting cells by expressing MHC class II molecules, which establishes the immune reaction in the tissue.

Cytokines and chemokines attract and accumulate immune cells, i.e. activated T- and B cells, monocytes and macrophages from activated fibroblast-like synoviocytes, in the joint space. By signalling through RANKL and RANK, they eventually trigger osteoclast production, which degrades bone tissue.

X-rays of the hands and feet are generally performed when many joints affected. In RA, there may be no changes in the early stages of the disease or the x-ray may show osteopenia near the joint, soft tissue swelling, and a smaller than normal joint space. As the disease advances, there may be bony erosions and subluxation. Other medical imaging techniques such as magnetic resonance imaging (MRI) and ultrasound are also used in RA.

Technical advances in ultrasonography like high-frequency transducers (10 MHz or higher) have improved the spatial resolution of ultrasound images depicting 20% more erosions than conventional radiography. Color Doppler and power Doppler ultrasound are useful in assessing the degree of synovial inflammation as they can show vascular signals of active synovitis. This is important, since in the early stages of RA, the synovium is primarily affected, and synovitis seems to be the best predictive marker of future joint damage.

These new classification criteria overruled the "old" ACR criteria of 1987 and are adapted for early RA diagnosis. The "new" classification criteria, jointly published by the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) establish a point value between 0 and 10. Four areas are covered in the diagnosis:

joint involvement, designating the metacarpophalangeal joints, proximal interphalangeal joints, the interphalangeal joint of the thumb, second through fifth metatarsophalangeal joint and wrist as small joints, and shoulders, elbows, hip joints, knees, and ankles as large joints:

The new criteria accommodate to the growing understanding of RA and the improvements in diagnosing RA and disease treatment. In the "new" criteria, serology and autoimmune diagnostics carries major weight, as ACPA detection is appropriate to diagnose the disease in an early state, before joints destructions occur. Destruction of the joints viewed in radiological images was a significant point of the ACR criteria from 1987.

Crystal induced arthritis (gout, and pseudogout) – usually involves particular joints (knee, MTP1, heels) and can be distinguished with an aspiration of joint fluid if in doubt. Redness, asymmetric distribution of affected joints, pain occurs at night and the starting pain is less than an hour with gout.

Osteoarthritis – distinguished with X-rays of the affected joints and blood tests, older age, starting pain less than an hour, asymmetric distribution of affected joints and pain worsens when using joint for longer periods.

Reactive arthritis – asymmetrically involves heel, sacroiliac joints and large joints of the leg. It is usually associated with urethritis, conjunctivitis, iritis, painless buccal ulcers, and keratoderma blennorrhagica.

Axial spondyloarthritis (including ankylosing spondylitis) – this involves the spine, although an RA-like symmetrical small-joint polyarthritis may occur in the context of this condition.

Hepatitis C – RA-like symmetrical small-joint polyarthritis may occur in the context of this condition. Hepatitis C may also induce rheumatoid factor auto-antibodies.

DAS28: Disease Activity Score of 28 joints (DAS28) is widely used as an indicator of RA disease activity and response to treatment. Joints included are (bilaterally): proximal interphalangeal joints (10 joints), metacarpophalangeal joints (10), wrists (2), elbows (2), shoulders (2) and knees (2). When looking at these joints, both the number of joints with tenderness upon touching (TEN28) and swelling (SW28) are counted. The erythrocyte sedimentation rate (ESR) is measured and the affected person makes a subjective assessment (SA) of disease activity during the preceding 7 days on a scale between 0 and 100, where 0 is "no activity" and 100 is "highest activity possible". With these parameters, DAS28 is calculated as:

Especially for affected fingers, hands, and wrists, synovectomy may be needed to prevent pain or tendon rupture when drug treatment has failed. Severely affected joints may require joint replacement surgery, such as knee replacement. Postoperatively, physiotherapy is always necessary.: 1080, 1103 There is insufficient evidence to support surgical treatment on arthritic shoulders.

There has been a growing interest in the role of long-chain omega-3 polyunsaturated fatty acids to reduce inflammation and alleviate the symptoms of RA. Metabolism of omega-3 polyunsaturated fatty acids produces docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which inhibits pro-inflammatory eicosanoids and cytokines (TNF-a, IL-1b and IL-6), decreasing both lymphocyte proliferation and reactive oxygen species.Gamma-linolenic acid, an omega-6 fatty acid, may reduce pain, tender joint count and stiffness, and is generally safe.omega-3 polyunsaturated fatty acids (found in fish oil, flax oil and hemp oil), a meta-analysis reported a favorable effect on pain, although confidence in the effect was considered moderate. The same review reported less inflammation but no difference in joint function.leukotriene4 (LTB4) was lowered in people with rheumatoid arthritis but not in those with non-autoimmune chronic diseases. (LTB4) increases vascular permeabiltity and stimulates other inflammatory substances.

Rheumatoid arthritis is derived from the Greek word ῥεύμα-rheuma (nom.), ῥεύματος-rheumatos (gen.) ("flow, current"). The suffix -oid ("resembling") gives the translation as joint inflammation that resembles rheumatic fever. Rhuma which means watery discharge might refer to the fact that the joints are swollen or that the disease may be made worse by wet weather.

The fibroblast-like synoviocytes have a prominent role in the pathogenic processes of the rheumatic joints, and therapies that target these cells are emerging as promising therapeutic tools, raising hope for future applications in rheumatoid arthritis.

Landré-Beauvais AJ (1800). La goutte asthénique primitive (doctoral thesis). Paris. reproduced in Landré-Beauvais AJ (March 2001). "The first description of rheumatoid arthritis. Unabridged text of the doctoral dissertation presented in 1800". Joint, Bone, Spine. 68 (2): 130–143. doi:10.1016/S1297-319X(00)00247-5. PMID 11324929.

Cutolo M, Kitas GD, van Riel PL (February 2014). "Burden of disease in treated rheumatoid arthritis patients: going beyond the joint". Seminars in Arthritis and Rheumatism. 43 (4): 479–488. doi:10.1016/j.semarthrit.2013.08.004. PMID 24080116.

Wasserman BR, Moskovich R, Razi AE (2011). "Rheumatoid arthritis of the cervical spine--clinical considerations" (PDF). Bulletin of the NYU Hospital for Joint Diseases. 69 (2): 136–148. PMID 22035393.

Guillot X, Semerano L, Saidenberg-Kermanac"h N, Falgarone G, Boissier MC (December 2010). "Vitamin D and inflammation". Joint, Bone, Spine. 77 (6): 552–557. doi:10.1016/j.jbspin.2010.09.018. PMID 21067953.

In dogs, hip dysplasia is an abnormal formation of the hip socket that, in its more severe form, can eventually cause lameness and arthritis of the joints. It is a genetic (polygenic) trait that is affected by environmental factors. It is common in many dog breeds, particularly the larger breeds, and is the most common single cause of arthritis of the hips.

During growth, both the ball (the head of the femur, or thighbone) and the socket in the pelvis (acetabulum) must grow at equal rates. In hip dysplasia, this uniform growth during puppyhood does not occur. The result is laxity (looseness) of the joint, followed by degenerative joint disease (DJD) or osteoarthritis (OA), which is the body"s attempt to stabilize the loose hip joint.

In the normal anatomy of the hip joint, the almost spherical end of the femur head (the caput, or caput ossis femoris) fits into the acetabulum (a concave socket located in the pelvis). The bony surfaces of the femur head and of the acetabulum are covered by cartilage. While bones provide the strength necessary to support body weight, cartilage ensures a smooth fit and a wide range of motion. Normal hip function can be affected by congenital conditions such as dysplasia, trauma, and by acquired diseases such as osteoarthritis and rheumatoid arthritis.

The hip could have major contractions from dysplasias. The caput is not deeply and tightly held by the acetabulum. Instead of being a snug fit, it is a loose fit, or a partial fit. Secondly, the caput or acetabulum are not smooth and round, but are misshapen, causing abnormal wear and tear or friction within the joint as it moves.cartilage. However, cartilage repair is a relatively slow process, the tissue being avascular, so the joint may suffer degradation due to the abnormal wear and tear, or may not support the body weight as intended. The joint becomes inflamed and a cycle of cartilage damage, inflammation and pain commences. This is a self-fueling process, in that the more the joint becomes damaged, the more damage it will cause to the surrounding tissues and bones. The inflammation also causes further damage. The bones of the joint may also develop osteoarthritis, visible on a radiograph as small outcrops of bone, which further degrade the joint.

The underlying deformity of the joint may get worse over time, or may remain static. A dog may have good radiographs and yet be in pain, or may have very poor radiographs and have no apparent pain issues. The hip condition is only one factor to determine the extent to which dysplasia is causing pain or affecting the quality of life. In mild to moderate dysplasia it is often the secondary effects of abnormal wear and tear or arthritis, rather than dysplasia itself, which is the direct causes of visible problems.

To reduce pain, the animal will typically reduce its movement of that hip. This may be visible as "bunny hopping", where both legs move together, or less dynamic movement (running, jumping), or stiffness. Since the hip cannot move fully, the body compensates by adapting its use of the spine, often causing spinal, stifle (a dog"s knee joint), or soft tissue problems to arise.

PennHIP requires the dog to be anesthetized. Three radiographs are taken to measure the hip joint laxity. A score between 0-1 is assigned, with 0 being very tight hips and 1 being very loose. The score is based on a measurement of the hip"s distraction index (DI). The distraction index is an indication of the "percent out of joint" that the femoral head is displaced from the acetabulum. For example, a DI of 0.15 means that the head of the femur is 15% out of joint.

Each hip joint is assessed by a BVA panel of experts that assign points based on nine aspects of the joint. The degree to which a dog is affected by hip dysplasia is represented by a score given to each hip. Scores for each hip are added together to get an overall hip score. Score ranges from zero to 106 (zero to 53 for each hip), with a score of zero representing the least degree of hip dysplasia and 53 representing the most.

A dog may misuse its rear legs, or adapt its gait, to compensate for pain in the forelimbs, notably osteoarthritis, osteochondritis (OCD) or shoulder or elbow dysplasia, as well as pain in the hocks and stifles or spinal issues. It is important to rule out other joint and bodily issues before concluding that only hip dysplasia is present. Even if some hip dysplasia is present, it is possible for other conditions to co-exist or be masked by it.

If the problem cannot be controlled with medications, then often surgery is considered. There are traditionally two types of surgery - those which reshape the joint to reduce pain or help movement, and hip replacement which completely replaces the damaged hip with an artificial joint, similar to human hip replacements.

Glucosamine and chondroitin sulfate are nutraceuticals that can also be added into the diet to help treat osteoarthritis caused by hip dysplasia. Both nutraceuticals help with improvement of cartilage, joint health and repairing of tissues. A glucosamine-based nutritional supplement may give the body additional raw materials used in joint repair. Glucosamine can take 3–4 weeks to start showing its effects, so the trial period for medication is usually at least 3–5 weeks. In vitro, glucosamine has been shown to have negative effects on cartilage cells.

Another nutrient that can help improve the structural support of the body is vitamin C. Vitamin C contributes to the building blocks of collagen that can help to strengthen the joints.

Triple pelvic osteotomy (TPO) involves bone cuts in the pelvis so that the socket portion of the joint can be rotated over the ball; the bones are then stabilized with a bone plate. This procedure is indicated for dogs under 10 months of age. A TPO can be performed to reestablish joint stability and encourage normal joint development. This procedure is not indicated if osteoarthritis is already present. Recovery time is about six weeks.

Hip replacement has the highest rate of success, especially in severe cases, since it completely replaces the faulty joint. It usually restores complete mobility if no other joint is affected, and also completely prevents recurrence. It is ideal for dogs over 10 months old that already have established osteoarthritis and can no longer be medically managed.

Juvenile pubic symphysiodesis (JPS) is a procedure for very young dogs that manipulates the way the pelvis grows to create a tighter hip. It involves cauterizing the growth plates of the pelvis to halt vertical growth. To compensate, the rest of the pelvis grows outward, in a manner which enhances the "socket" of the hip and provides better support than the dog would have had naturally. Since it relies on growth in puppyhood, it has a very tight window for surgery – between 4 and 5 months old. This is compatible with hip scoring of puppies at 4 months.

Powers, David M. W. (2012). "The Problem with Kappa". Conference of the European Chapter of the Association for Computational Linguistics (EACL2012) Joint ROBUS-UNSUP Workshop.

Brooks, Harold; Brown, Barb; Ebert, Beth; Ferro, Chris; Jolliffe, Ian; Koh, Tieh-Yong; Roebber, Paul; Stephenson, David (2015-01-26). "WWRP/WGNE Joint Working Group on Forecast Verification Research". Collaboration for Australian Weather and Climate Research. World Meteorological Organisation. Retrieved 2019-07-17.

Brooks, Harold; Brown, Barb; Ebert, Beth; Ferro, Chris; Jolliffe, Ian; Koh, Tieh-Yong; Roebber, Paul; Stephenson, David (2015-01-26). "WWRP/WGNE Joint Working Group on Forecast Verification Research". Collaboration for Australian Weather and Climate Research. World Meteorological Organisation. Retrieved 2019-07-17.

In humans, the only true anatomical joints between the shoulder girdle and the axial skeleton are the sternoclavicular joints on each side. No anatomical joint exists between each scapula and the rib cage; instead the muscular connection or physiological joint between the two permits great mobility of the shoulder girdle compared to the compact pelvic girdle; because the upper limb is not usually involved in weight bearing, its stability has been sacrificed in exchange for greater mobility. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular.

The shoulder girdle is the anatomical mechanism that allows for all upper arm and shoulder movement in humans. clavicle and scapula and allow for the motion of the sternoclavicular joint (connection between sternum and clavicle) and acromioclavicular joint (connection between clavicle and scapula).trapezius muscle (upper, middle, and lower), levator scapulae muscle, rhomboid muscles (major and minor), serratus anterior muscle, and pectoralis minor muscle.

The shoulder girdle is a complex of 5 joints that can be divided into two groups. 3 of these joints are true anatomical joints, while 2 are physiological ("false") joints.: 20

In the first group, the scapulohumeral or glenohumeral joint is the anatomical joint mechanically linked to the physiological subdeltoid or suprahumeral joint (the "second shoulder joint") so that movements in the suprahumeral joint results in movements in the glenohumeral joint.

In the second group, the scapulocostal or scapulothoracic joint is the important physiological joint that can not function without the two anatomical joints in the group, the acromioclavicular and sternoclavicular joints, i.e. they join both ends of the clavicle.: 20

The glenohumeral joint is the articulation between the head of the humerus and the glenoid cavity of the scapula. It is a ball and socket type of synovial joint with three rotatory and three translatory degrees of freedom. The glenohumeral joint allows for adduction, abduction, medial and lateral rotation, flexion and extension of the arm.

The acromioclavicular joint is the articulation between the acromion process of the scapula and the lateral end of the clavicle. It is a plane type of synovial joint. The acromion of the scapula rotates on the acromial end of the clavicle.

The sternoclavicular joint is the articulation of the manubrium of the sternum and the first costal cartilage with the medial end of the clavicle. It is a saddle type of synovial joint but functions as a plane joint. The sternoclavicular joint accommodates a wide range of scapula movements and can be raised to a 60° angle.

The scapulocostal joint (also known as the scapulothoracic joint) is a physiological joint formed by an articulation of the anterior scapula and the posterior thoracic rib cage. It is musculotendinous in nature and is formed predominantly by the trapezius, rhomboids and serratus anterior muscles. The pectoralis minor also plays a role in its movements. The gliding movements at the scapulocostal joint are elevation, depression, retraction, protraction and superior and inferior rotation of the scapula. Disorders of the scapulocostal joint are not very common and usually restricted to snapping scapula.

The suprahumeral joint (also known as the subacromial joint) is a physiological joint formed by an articulation of the coracoacromial ligament and the head of the humerus. It is formed by the gap between the humerus and the acromion process of the scapula. This space is filled mostly by the subacromial bursa and the tendon of supraspinatus. This joint plays a role during complex movements while the arm is fully flexed at the glenohumeral joint, such as changing a lightbulb, or painting a ceiling.

From its neutral position, the shoulder girdle can be rotated about an imaginary vertical axis at the medial end of the clavicle (the sternoclavicular joint). Throughout this movement the scapula is rotated around the chest wall so that it moves 15 centimetres (5.9 in) laterally and the glenoid cavity is rotated 40–45° in the horizontal plane. When the scapula is moved medially it lies in a frontal plane with the glenoid cavity facing directly laterally. At this position, the lateral end of the clavicle is rotated posteriorly so that the angle at the acromioclavicular joint opens up slightly. When the scapula is moved laterally it lies in a sagittal plane with the glenoid cavity facing anteriorly. At this position, the lateral end of the clavicle is rotated anteriorly so that the clavicle lies in a frontal plane. While this slightly closes the angle between the clavicle and the scapula, it also widens the shoulder.: 40

Shoulders are a common place for tissue injuries, especially if the person plays overhead sports such as tennis, volleyball, baseball, swimming, etc. According to Bahr"s major injury related statistics, shoulder dislocations or subluxations account for 4% of injuries in adults ages 20–30 and 20% of shoulder injuries are fractures.clavicle, ligamentous sprains such as AC joint or GH ligaments, rotator cuff injuries, different labral tears, and other acute or chronic conditions related to shoulder anatomy.

Physiological joints are called "false" joints because they lack the characteristics of "true" anatomical joints, such as tendons and a capsule, but they are still joints because the gliding movements they provide play an important biomechanical role. (Roy 2009, Focused anatomy)

Housepets, particularly dogs and cats in industrialized societies, are also highly susceptible to obesity. Overweight pets have been shown to be at a higher risk of developing diabetes, liver problems, joint pain, kidney failure, and cancer. Lack of exercise and high-caloric diets are considered to be the primary contributors to pet obesity.

In 2010, three factors drove a significant increase in RFID usage: decreased cost of equipment and tags, increased performance to a reliability of 99.9%, and a stable international standard around HF and UHF passive RFID. The adoption of these standards were driven by EPCglobal, a joint venture between GS1 and GS1 US, which were responsible for driving global adoption of the barcode in the 1970s and 1980s. The EPCglobal Network was developed by the Auto-ID Center.

In 2004, school authorities in the Japanese city of Osaka made a decision to start chipping children"s clothing, backpacks, and student IDs in a primary school.Doncaster, England, piloted a monitoring system designed to keep tabs on pupils by tracking radio chips in their uniforms.St Charles Sixth Form College in west London, England, starting in 2008, uses an RFID card system to check in and out of the main gate, to both track attendance and prevent unauthorized entrance. Similarly, Whitcliffe Mount School in Cleckheaton, England, uses RFID to track pupils and staff in and out of the building via a specially designed card. In the Philippines, during 2012, some schools already

EPCglobal, a joint venture between GS1 and GS1 US, is working on international standards for the use of mostly passive RFID and the Electronic Product Code (EPC) in the identification of many items in the supply chain for companies worldwide.

On May 20, 1949, all cryptologic activities were centralized under a national organization called the Armed Forces Security Agency (AFSA).U.S. Department of Defense under the command of the Joint Chiefs of Staff.military intelligence units.communications intelligence and failed to coordinate with civilian agencies that shared its interests such as the Department of State, Central Intelligence Agency (CIA) and the Federal Bureau of Investigation (FBI).Harry S. Truman ordered a panel to investigate how AFSA had failed to achieve its goals. The results of the investigation led to improvements and its redesignation as the National Security Agency.

NSA/CSS Threat Operations Center (NTOC), which is the primary NSA/CSS partner for Department of Homeland Security response to cyber incidents. The NTOC establishes real-time network awareness and threat characterization capabilities to forecast, alert, and attribute malicious activity and enable the coordination of Computer Network Operations. The NTOC was established in 2004 as a joint Information Assurance and Signals Intelligence project.

Thailand is the site of at least two US SIGINT collection stations. One is at the US Embassy in Bangkok, a joint NSA-CIA Special Collection Service (SCS) unit. It presumably eavesdrops on foreign embassies, governmental communications, and other targets of opportunity.

In March 2014, Army General Martin Dempsey, Chairman of the Joint Chiefs of Staff, told the House Armed Services Committee, "The vast majority of the documents that Snowden ... exfiltrated from our highest levels of security ... had nothing to do with exposing government oversight of domestic activities. The vast majority of those were related to our military capabilities, operations, tactics, techniques, and procedures."

"JITC Networks, Transmissions, and Integration Division Electronic Key Management System (EKMS)". U.S. Department of Defense: Defense Information Systems Agency: Joint Interoperability Certifier. February 1991. Archived from the original on May 15, 2013. Retrieved June 30, 2013.

This Manual of Style (MoS or MOS) is the style manual for all English Wikipedia articles (though provisions related to accessibility apply across the entire project, not just to articles). This primary page is supported by further detail pages, which are cross-referenced here and listed at Wikipedia:Manual of Style/Contents. If any contradiction arises, this page has precedence.

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