rongsheng lee free sample

Shaohong Feng, Guojie Zhang, Yang Zhou designed and directed the project; Peter Andrew Hosner selected and provided samples for analysis; Daniel Bilyeli Øksnebjerg organized and managed the project; Alivia Lee Price extracted the DNA from the sample; Guangji Chen performed genome assembly; Xuemei Li and Rongsheng Gao analyzed the data; Xuemei Li and Rongsheng Gao wrote the manuscript with other authors’ help; Shaohong Feng, Guojie Zhang, Yang Zhou and Peter Andrew Hosner revised the manuscript. All authors read and approved the final manuscript. Xuemei Li and Rongsheng Gao made the same contribution.

Department of Physiology and Biophysics, University of California, Irvine, CA 92697, USA; E-Mails: g.yao@uci.edu (G.Y.); kwanglee@uci.edu (K.L.); sgu5@its.jnj.com (S.G.); kwokhl@uci.edu (K.H.L.)

We thank Robbin Newlin for assistance with tissue preparation and immunostaining. We thank Core H of the Consortium for Functional Glycomics (CFG) for glycan array screening. This work was partly supported by National Institute of Allergy and Infectious Diseases (NIAID) grant R01AI091823 to Rongsheng Jin.

17.Lee, K.; Gu, S.; Jin, L.; Le, T.T.; Cheng, L.W.; Strotmeier, J.; Kruel, A.M.; Yao, G.; Perry, K.; et al. Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity. PLoSPathog. 2013, 9, e1003690.

23.Nishikawa, A.; Uotsu, N.; Arimitsu, H.; Lee, J.C.; Miura, Y.; Fujinaga, Y.; Nakada, H.; Watanabe, T.; Ohyama, T.; Sakano, Y.; et al. The receptor and transporter for internalization of Clostridium botulinum type C progenitor toxin into HT-29 cells. Biochem. Biophys. Res. Commun. 2004, 319, 327-333.

Gender has been proposed as an important factor in influencing Internet use and its outcomes regarding mental health (e.g., 8). Evidence has suggested that males have a predilection toward activities that involve explosive action and combat, while females are drawn toward activities that are more social and communication focused (25). Females received more family supervision, which may prevent them from developing Internet addiction (26). In a more recent study, female video game addicts displayed significantly more somatic difficulties than male addicts (4). They further argued that female addicts may be uniquely at risk for negative physical health outcomes and sleep disturbances (4). Significant gender difference was also revealed on the association between family function and Internet addiction among adolescence (27). Females showed more negative consequences of its maladaptive mobile phone use (28). These studies highlighted the need to explore gender differences in mobile game addition and mental health problems further.

1. Su YS, Chiang WL, Lee CTJ, Chang HC. The effect of flow experience on player loyalty in mobile game application. Comput Hum Behav. (2016) 63:240–8. doi: 10.1016/j.chb.2016.05.049

41. Whang LS, Ph D, Lee S, Ph D, Chang G. Internet over-users" psychological profiles: a behavior sampling analysis on internet addiction. Cyber Psychol Behav. (2003) 6:143–51. doi: 10.1089/109493103321640338

Citation:Lee K, Gu S, Jin L, Le TTN, Cheng LW, Strotmeier J, et al. (2013) Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity. PLoS Pathog 9(10):

Copyright: © 2013 Lee et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.